SrasV1, 2020, Analysis, bibRecord, 000836

Clinical and computed tomographic imaging features of novel coronavirus pneumonia caused by SARS-CoV-2

Identifieur interne : 000836 ( 2020/Analysis ); précédent : 000835; suivant : 000837

Clinical and computed tomographic imaging features of novel coronavirus pneumonia caused by SARS-CoV-2

Auteurs : Yu-Huan Xu [République populaire de Chine] ; Jing-Hui Dong [République populaire de Chine] ; Wei-Min An [République populaire de Chine] ; Xiao-Yan Lv [République populaire de Chine] ; Xiao-Ping Yin [République populaire de Chine] ; Jian-Zeng Zhang [République populaire de Chine] ; Li Dong [République populaire de Chine] ; Xi Ma [République populaire de Chine] ; Hong-Jie Zhang [République populaire de Chine] ; Bu-Lang Gao [République populaire de Chine]

Source :

The Journal of Infection [ 0163-4453 ] ; 2020.

RBID : PMC:7102535

Descripteurs français

KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Enfant, Enfant d'âge préscolaire, Femelle, Fièvre, Humains, Infections à coronavirus (diagnostic), Infections à coronavirus (imagerie diagnostique), Infections à coronavirus (physiopathologie), Jeune adulte, Mâle, Pandémies, Pneumopathie virale (imagerie diagnostique), Pneumopathie virale (physiopathologie), Poumon (imagerie diagnostique), Sujet âgé, Sujet âgé de 80 ans ou plus, Techniques de laboratoire clinique, Tomodensitométrie, Toux, Études rétrospectives.
MESH :
- diagnostic : Infections à coronavirus.
- imagerie diagnostique : Infections à coronavirus, Pneumopathie virale, Poumon.
- physiopathologie : Infections à coronavirus, Pneumopathie virale.
- Adolescent, Adulte, Adulte d'âge moyen, Enfant, Enfant d'âge préscolaire, Femelle, Fièvre, Humains, Jeune adulte, Mâle, Pandémies, Sujet âgé, Sujet âgé de 80 ans ou plus, Techniques de laboratoire clinique, Tomodensitométrie, Toux, Études rétrospectives.

English descriptors

KwdEn :
- Adolescent, Adult, Aged, Aged, 80 and over, Betacoronavirus, Child, Child, Preschool, Clinical Laboratory Techniques, Coronavirus Infections (diagnosis), Coronavirus Infections (diagnostic imaging), Coronavirus Infections (physiopathology), Cough, Female, Fever, Humans, Lung (diagnostic imaging), Male, Middle Aged, Pandemics, Pneumonia, Viral (diagnostic imaging), Pneumonia, Viral (physiopathology), Retrospective Studies, Tomography, X-Ray Computed, Young Adult.
MESH :
- diagnosis : Coronavirus Infections.
- diagnostic imaging : Coronavirus Infections, Lung, Pneumonia, Viral.
- physiopathology : Coronavirus Infections, Pneumonia, Viral.
- Adolescent, Adult, Aged, Aged, 80 and over, Betacoronavirus, Child, Child, Preschool, Clinical Laboratory Techniques, Cough, Female, Fever, Humans, Male, Middle Aged, Pandemics, Retrospective Studies, Tomography, X-Ray Computed, Young Adult.

Abstract

SummaryPurpose

To investigate the clinical and imaging characteristics of computed tomography (CT) in novel coronavirus pneumonia (NCP) caused by SARS-CoV-2.

Materials and methods

A retrospective analysis was performed on the imaging findings of patients confirmed with COVID-19 pneumonia who had chest CT scanning and treatment after disease onset. The clinical and imaging data were analyzed.

Results

Fifty patients were enrolled, including mild type in nine, common in 28, severe in 10 and critically severe in the rest three. Mild patients (29 years) were significantly (P<0.03) younger than either common (44.5 years) or severe (54.7) and critically severe (65.7 years) patients, and common patients were also significantly (P<0.03) younger than severe and critically severe patients. Mild patients had low to moderate fever (<39.1 °C), 49 (98%) patients had normal or slightly reduced leukocyte count, 14 (28%) had decreased counts of lymphocytes, and 26 (52%) patients had increased C-reactive protein. Nine mild patients were negative in CT imaging. For all the other types of NCP, the lesion was in the right upper lobe in 30 cases, right middle lobe in 22, right lower lobe in 39, left upper lobe in 33 and left lower lobe in 36. The lesion was primarily located in the peripheral area under the pleura with possible extension towards the pulmonary hilum. Symmetrical lesions were seen in 26 cases and asymmetrical in 15. The density of lesion was mostly uneven with ground glass opacity as the primary presentation accompanied by partial consolidation and fibrosis.

Conclusion

CT imaging presentations of NCP are mostly patchy ground glass opacities in the peripheral areas under the pleura with partial consolidation which will be absorbed with formation of fibrotic stripes if improved. CT scanning provides important bases for early diagnosis and treatment of NCP.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102535

DOI: 10.1016/j.jinf.2020.02.017
PubMed: 32109443
PubMed Central: 7102535

Affiliations:

Links to Exploration step

PMC:7102535

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Clinical and computed tomographic imaging features of novel coronavirus pneumonia caused by SARS-CoV-2</title>
<author><name sortKey="Xu, Yu Huan" sort="Xu, Yu Huan" uniqKey="Xu Y" first="Yu-Huan" last="Xu">Yu-Huan Xu</name>
<affiliation wicri:level="1"><nlm:aff id="aff0001">Department of Radiology, The Fifth Medical Center of Chinese PLA General Hospital, 100 West Fourth Ring Road, Fengtai District, Beijing 100039, China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Radiology, The Fifth Medical Center of Chinese PLA General Hospital, 100 West Fourth Ring Road, Fengtai District, Beijing 100039</wicri:regionArea>
<placeName><settlement type="city">Pékin</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Dong, Jing Hui" sort="Dong, Jing Hui" uniqKey="Dong J" first="Jing-Hui" last="Dong">Jing-Hui Dong</name>
<affiliation wicri:level="1"><nlm:aff id="aff0001">Department of Radiology, The Fifth Medical Center of Chinese PLA General Hospital, 100 West Fourth Ring Road, Fengtai District, Beijing 100039, China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Radiology, The Fifth Medical Center of Chinese PLA General Hospital, 100 West Fourth Ring Road, Fengtai District, Beijing 100039</wicri:regionArea>
<placeName><settlement type="city">Pékin</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="An, Wei Min" sort="An, Wei Min" uniqKey="An W" first="Wei-Min" last="An">Wei-Min An</name>
<affiliation wicri:level="1"><nlm:aff id="aff0001">Department of Radiology, The Fifth Medical Center of Chinese PLA General Hospital, 100 West Fourth Ring Road, Fengtai District, Beijing 100039, China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Radiology, The Fifth Medical Center of Chinese PLA General Hospital, 100 West Fourth Ring Road, Fengtai District, Beijing 100039</wicri:regionArea>
<placeName><settlement type="city">Pékin</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lv, Xiao Yan" sort="Lv, Xiao Yan" uniqKey="Lv X" first="Xiao-Yan" last="Lv">Xiao-Yan Lv</name>
<affiliation wicri:level="1"><nlm:aff id="aff0001">Department of Radiology, The Fifth Medical Center of Chinese PLA General Hospital, 100 West Fourth Ring Road, Fengtai District, Beijing 100039, China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Radiology, The Fifth Medical Center of Chinese PLA General Hospital, 100 West Fourth Ring Road, Fengtai District, Beijing 100039</wicri:regionArea>
<placeName><settlement type="city">Pékin</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Yin, Xiao Ping" sort="Yin, Xiao Ping" uniqKey="Yin X" first="Xiao-Ping" last="Yin">Xiao-Ping Yin</name>
<affiliation wicri:level="1"><nlm:aff id="aff0002">CT/MRI Room, Affiliated Hospital of Hebei University, 212 Eastern Yuhua Road, Baoding, Hebei Province 071000, China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>CT/MRI Room, Affiliated Hospital of Hebei University, 212 Eastern Yuhua Road, Baoding, Hebei Province 071000</wicri:regionArea>
<wicri:noRegion>Hebei Province 071000</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Zhang, Jian Zeng" sort="Zhang, Jian Zeng" uniqKey="Zhang J" first="Jian-Zeng" last="Zhang">Jian-Zeng Zhang</name>
<affiliation wicri:level="1"><nlm:aff id="aff0001">Department of Radiology, The Fifth Medical Center of Chinese PLA General Hospital, 100 West Fourth Ring Road, Fengtai District, Beijing 100039, China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Radiology, The Fifth Medical Center of Chinese PLA General Hospital, 100 West Fourth Ring Road, Fengtai District, Beijing 100039</wicri:regionArea>
<placeName><settlement type="city">Pékin</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Dong, Li" sort="Dong, Li" uniqKey="Dong L" first="Li" last="Dong">Li Dong</name>
<affiliation wicri:level="1"><nlm:aff id="aff0003">Department of Radiology, Baoding City People's Hospital, Baoding, Hebei Province 071000, China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Radiology, Baoding City People's Hospital, Baoding, Hebei Province 071000</wicri:regionArea>
<wicri:noRegion>Hebei Province 071000</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ma, Xi" sort="Ma, Xi" uniqKey="Ma X" first="Xi" last="Ma">Xi Ma</name>
<affiliation wicri:level="1"><nlm:aff id="aff0002">CT/MRI Room, Affiliated Hospital of Hebei University, 212 Eastern Yuhua Road, Baoding, Hebei Province 071000, China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>CT/MRI Room, Affiliated Hospital of Hebei University, 212 Eastern Yuhua Road, Baoding, Hebei Province 071000</wicri:regionArea>
<wicri:noRegion>Hebei Province 071000</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Zhang, Hong Jie" sort="Zhang, Hong Jie" uniqKey="Zhang H" first="Hong-Jie" last="Zhang">Hong-Jie Zhang</name>
<affiliation wicri:level="1"><nlm:aff id="aff0004">Clinical College, Hebei University, Boding, Hebei Province, China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Clinical College, Hebei University, Boding, Hebei Province</wicri:regionArea>
<wicri:noRegion>Hebei Province</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Gao, Bu Lang" sort="Gao, Bu Lang" uniqKey="Gao B" first="Bu-Lang" last="Gao">Bu-Lang Gao</name>
<affiliation wicri:level="1"><nlm:aff id="aff0001">Department of Radiology, The Fifth Medical Center of Chinese PLA General Hospital, 100 West Fourth Ring Road, Fengtai District, Beijing 100039, China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Radiology, The Fifth Medical Center of Chinese PLA General Hospital, 100 West Fourth Ring Road, Fengtai District, Beijing 100039</wicri:regionArea>
<placeName><settlement type="city">Pékin</settlement>
</placeName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">32109443</idno>
<idno type="pmc">7102535</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102535</idno>
<idno type="RBID">PMC:7102535</idno>
<idno type="doi">10.1016/j.jinf.2020.02.017</idno>
<date when="2020">2020</date>
<idno type="wicri:Area/Pmc/Corpus">001182</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001182</idno>
<idno type="wicri:Area/Pmc/Curation">001182</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001182</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000332</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000332</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="RBID">pubmed:32109443</idno>
<idno type="wicri:Area/PubMed/Corpus">000728</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000728</idno>
<idno type="wicri:Area/PubMed/Curation">000728</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000728</idno>
<idno type="wicri:Area/PubMed/Checkpoint">000660</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000660</idno>
<idno type="wicri:Area/Ncbi/Merge">003252</idno>
<idno type="wicri:Area/Ncbi/Curation">003252</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">003252</idno>
<idno type="wicri:doubleKey">0163-4453:2020:Xu Y:clinical:and:computed</idno>
<idno type="wicri:Area/Main/Merge">000836</idno>
<idno type="wicri:Area/Main/Curation">000836</idno>
<idno type="wicri:Area/Main/Exploration">000836</idno>
<idno type="wicri:Area/2020/Extraction">000836</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Clinical and computed tomographic imaging features of novel coronavirus pneumonia caused by SARS-CoV-2</title>
<author><name sortKey="Xu, Yu Huan" sort="Xu, Yu Huan" uniqKey="Xu Y" first="Yu-Huan" last="Xu">Yu-Huan Xu</name>
<affiliation wicri:level="1"><nlm:aff id="aff0001">Department of Radiology, The Fifth Medical Center of Chinese PLA General Hospital, 100 West Fourth Ring Road, Fengtai District, Beijing 100039, China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Radiology, The Fifth Medical Center of Chinese PLA General Hospital, 100 West Fourth Ring Road, Fengtai District, Beijing 100039</wicri:regionArea>
<placeName><settlement type="city">Pékin</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Dong, Jing Hui" sort="Dong, Jing Hui" uniqKey="Dong J" first="Jing-Hui" last="Dong">Jing-Hui Dong</name>
<affiliation wicri:level="1"><nlm:aff id="aff0001">Department of Radiology, The Fifth Medical Center of Chinese PLA General Hospital, 100 West Fourth Ring Road, Fengtai District, Beijing 100039, China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Radiology, The Fifth Medical Center of Chinese PLA General Hospital, 100 West Fourth Ring Road, Fengtai District, Beijing 100039</wicri:regionArea>
<placeName><settlement type="city">Pékin</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="An, Wei Min" sort="An, Wei Min" uniqKey="An W" first="Wei-Min" last="An">Wei-Min An</name>
<affiliation wicri:level="1"><nlm:aff id="aff0001">Department of Radiology, The Fifth Medical Center of Chinese PLA General Hospital, 100 West Fourth Ring Road, Fengtai District, Beijing 100039, China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Radiology, The Fifth Medical Center of Chinese PLA General Hospital, 100 West Fourth Ring Road, Fengtai District, Beijing 100039</wicri:regionArea>
<placeName><settlement type="city">Pékin</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lv, Xiao Yan" sort="Lv, Xiao Yan" uniqKey="Lv X" first="Xiao-Yan" last="Lv">Xiao-Yan Lv</name>
<affiliation wicri:level="1"><nlm:aff id="aff0001">Department of Radiology, The Fifth Medical Center of Chinese PLA General Hospital, 100 West Fourth Ring Road, Fengtai District, Beijing 100039, China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Radiology, The Fifth Medical Center of Chinese PLA General Hospital, 100 West Fourth Ring Road, Fengtai District, Beijing 100039</wicri:regionArea>
<placeName><settlement type="city">Pékin</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Yin, Xiao Ping" sort="Yin, Xiao Ping" uniqKey="Yin X" first="Xiao-Ping" last="Yin">Xiao-Ping Yin</name>
<affiliation wicri:level="1"><nlm:aff id="aff0002">CT/MRI Room, Affiliated Hospital of Hebei University, 212 Eastern Yuhua Road, Baoding, Hebei Province 071000, China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>CT/MRI Room, Affiliated Hospital of Hebei University, 212 Eastern Yuhua Road, Baoding, Hebei Province 071000</wicri:regionArea>
<wicri:noRegion>Hebei Province 071000</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Zhang, Jian Zeng" sort="Zhang, Jian Zeng" uniqKey="Zhang J" first="Jian-Zeng" last="Zhang">Jian-Zeng Zhang</name>
<affiliation wicri:level="1"><nlm:aff id="aff0001">Department of Radiology, The Fifth Medical Center of Chinese PLA General Hospital, 100 West Fourth Ring Road, Fengtai District, Beijing 100039, China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Radiology, The Fifth Medical Center of Chinese PLA General Hospital, 100 West Fourth Ring Road, Fengtai District, Beijing 100039</wicri:regionArea>
<placeName><settlement type="city">Pékin</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Dong, Li" sort="Dong, Li" uniqKey="Dong L" first="Li" last="Dong">Li Dong</name>
<affiliation wicri:level="1"><nlm:aff id="aff0003">Department of Radiology, Baoding City People's Hospital, Baoding, Hebei Province 071000, China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Radiology, Baoding City People's Hospital, Baoding, Hebei Province 071000</wicri:regionArea>
<wicri:noRegion>Hebei Province 071000</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ma, Xi" sort="Ma, Xi" uniqKey="Ma X" first="Xi" last="Ma">Xi Ma</name>
<affiliation wicri:level="1"><nlm:aff id="aff0002">CT/MRI Room, Affiliated Hospital of Hebei University, 212 Eastern Yuhua Road, Baoding, Hebei Province 071000, China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>CT/MRI Room, Affiliated Hospital of Hebei University, 212 Eastern Yuhua Road, Baoding, Hebei Province 071000</wicri:regionArea>
<wicri:noRegion>Hebei Province 071000</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Zhang, Hong Jie" sort="Zhang, Hong Jie" uniqKey="Zhang H" first="Hong-Jie" last="Zhang">Hong-Jie Zhang</name>
<affiliation wicri:level="1"><nlm:aff id="aff0004">Clinical College, Hebei University, Boding, Hebei Province, China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Clinical College, Hebei University, Boding, Hebei Province</wicri:regionArea>
<wicri:noRegion>Hebei Province</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Gao, Bu Lang" sort="Gao, Bu Lang" uniqKey="Gao B" first="Bu-Lang" last="Gao">Bu-Lang Gao</name>
<affiliation wicri:level="1"><nlm:aff id="aff0001">Department of Radiology, The Fifth Medical Center of Chinese PLA General Hospital, 100 West Fourth Ring Road, Fengtai District, Beijing 100039, China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Radiology, The Fifth Medical Center of Chinese PLA General Hospital, 100 West Fourth Ring Road, Fengtai District, Beijing 100039</wicri:regionArea>
<placeName><settlement type="city">Pékin</settlement>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j">The Journal of Infection</title>
<idno type="ISSN">0163-4453</idno>
<idno type="eISSN">1532-2742</idno>
<imprint><date when="2020">2020</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Betacoronavirus</term>
<term>Child</term>
<term>Child, Preschool</term>
<term>Clinical Laboratory Techniques</term>
<term>Coronavirus Infections (diagnosis)</term>
<term>Coronavirus Infections (diagnostic imaging)</term>
<term>Coronavirus Infections (physiopathology)</term>
<term>Cough</term>
<term>Female</term>
<term>Fever</term>
<term>Humans</term>
<term>Lung (diagnostic imaging)</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Pandemics</term>
<term>Pneumonia, Viral (diagnostic imaging)</term>
<term>Pneumonia, Viral (physiopathology)</term>
<term>Retrospective Studies</term>
<term>Tomography, X-Ray Computed</term>
<term>Young Adult</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent</term>
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Enfant</term>
<term>Enfant d'âge préscolaire</term>
<term>Femelle</term>
<term>Fièvre</term>
<term>Humains</term>
<term>Infections à coronavirus (diagnostic)</term>
<term>Infections à coronavirus (imagerie diagnostique)</term>
<term>Infections à coronavirus (physiopathologie)</term>
<term>Jeune adulte</term>
<term>Mâle</term>
<term>Pandémies</term>
<term>Pneumopathie virale (imagerie diagnostique)</term>
<term>Pneumopathie virale (physiopathologie)</term>
<term>Poumon (imagerie diagnostique)</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Techniques de laboratoire clinique</term>
<term>Tomodensitométrie</term>
<term>Toux</term>
<term>Études rétrospectives</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Coronavirus Infections</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Infections à coronavirus</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnostic imaging" xml:lang="en"><term>Coronavirus Infections</term>
<term>Lung</term>
<term>Pneumonia, Viral</term>
</keywords>
<keywords scheme="MESH" qualifier="imagerie diagnostique" xml:lang="fr"><term>Infections à coronavirus</term>
<term>Pneumopathie virale</term>
<term>Poumon</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathologie" xml:lang="fr"><term>Infections à coronavirus</term>
<term>Pneumopathie virale</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Coronavirus Infections</term>
<term>Pneumonia, Viral</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Betacoronavirus</term>
<term>Child</term>
<term>Child, Preschool</term>
<term>Clinical Laboratory Techniques</term>
<term>Cough</term>
<term>Female</term>
<term>Fever</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Pandemics</term>
<term>Retrospective Studies</term>
<term>Tomography, X-Ray Computed</term>
<term>Young Adult</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term>
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Enfant</term>
<term>Enfant d'âge préscolaire</term>
<term>Femelle</term>
<term>Fièvre</term>
<term>Humains</term>
<term>Jeune adulte</term>
<term>Mâle</term>
<term>Pandémies</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Techniques de laboratoire clinique</term>
<term>Tomodensitométrie</term>
<term>Toux</term>
<term>Études rétrospectives</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><title>Summary</title>
<sec><title>Purpose</title>
<p>To investigate the clinical and imaging characteristics of computed tomography (CT) in novel coronavirus pneumonia (NCP) caused by SARS-CoV-2.</p>
</sec>
<sec><title>Materials and methods</title>
<p>A retrospective analysis was performed on the imaging findings of patients confirmed with COVID-19 pneumonia who had chest CT scanning and treatment after disease onset. The clinical and imaging data were analyzed.</p>
</sec>
<sec><title>Results</title>
<p>Fifty patients were enrolled, including mild type in nine, common in 28, severe in 10 and critically severe in the rest three. Mild patients (29 years) were significantly (<italic>P</italic>
<0.03) younger than either common (44.5 years) or severe (54.7) and critically severe (65.7 years) patients, and common patients were also significantly (<italic>P</italic>
<0.03) younger than severe and critically severe patients. Mild patients had low to moderate fever (<39.1 °C), 49 (98%) patients had normal or slightly reduced leukocyte count, 14 (28%) had decreased counts of lymphocytes, and 26 (52%) patients had increased C-reactive protein. Nine mild patients were negative in CT imaging. For all the other types of NCP, the lesion was in the right upper lobe in 30 cases, right middle lobe in 22, right lower lobe in 39, left upper lobe in 33 and left lower lobe in 36. The lesion was primarily located in the peripheral area under the pleura with possible extension towards the pulmonary hilum. Symmetrical lesions were seen in 26 cases and asymmetrical in 15. The density of lesion was mostly uneven with ground glass opacity as the primary presentation accompanied by partial consolidation and fibrosis.</p>
</sec>
<sec><title>Conclusion</title>
<p>CT imaging presentations of NCP are mostly patchy ground glass opacities in the peripheral areas under the pleura with partial consolidation which will be absorbed with formation of fibrotic stripes if improved. CT scanning provides important bases for early diagnosis and treatment of NCP.</p>
</sec>
</div>
</front>
<back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Huang, C" uniqKey="Huang C">C. Huang</name>
</author>
<author><name sortKey="Wang, Y" uniqKey="Wang Y">Y. Wang</name>
</author>
<author><name sortKey="Li, X" uniqKey="Li X">X. Li</name>
</author>
<author><name sortKey="Ren, L" uniqKey="Ren L">L. Ren</name>
</author>
<author><name sortKey="Zhao, J" uniqKey="Zhao J">J. Zhao</name>
</author>
<author><name sortKey="Hu, Y" uniqKey="Hu Y">Y. Hu</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kui, L" uniqKey="Kui L">L. Kui</name>
</author>
<author><name sortKey="Fang, Y Y" uniqKey="Fang Y">Y.Y. Fang</name>
</author>
<author><name sortKey="Deng, Y" uniqKey="Deng Y">Y. Deng</name>
</author>
<author><name sortKey="Liu, W" uniqKey="Liu W">W. Liu</name>
</author>
<author><name sortKey="Wang, M F" uniqKey="Wang M">M.F. Wang</name>
</author>
<author><name sortKey="Ma, J P" uniqKey="Ma J">J.P. Ma</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wang, D" uniqKey="Wang D">D. Wang</name>
</author>
<author><name sortKey="Hu, B" uniqKey="Hu B">B. Hu</name>
</author>
<author><name sortKey="Hu, C" uniqKey="Hu C">C. Hu</name>
</author>
<author><name sortKey="Zhu, F" uniqKey="Zhu F">F. Zhu</name>
</author>
<author><name sortKey="Liu, X" uniqKey="Liu X">X. Liu</name>
</author>
<author><name sortKey="Zhang, J" uniqKey="Zhang J">J. Zhang</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Jiang, X" uniqKey="Jiang X">X. Jiang</name>
</author>
<author><name sortKey="Rayner, S" uniqKey="Rayner S">S. Rayner</name>
</author>
<author><name sortKey="Luo, M H" uniqKey="Luo M">M.H Luo</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lorusso, A" uniqKey="Lorusso A">A. Lorusso</name>
</author>
<author><name sortKey="Calistri, P" uniqKey="Calistri P">P. Calistri</name>
</author>
<author><name sortKey="Petrini, A" uniqKey="Petrini A">A. Petrini</name>
</author>
<author><name sortKey="Savini, G" uniqKey="Savini G">G. Savini</name>
</author>
<author><name sortKey="Decaro, N" uniqKey="Decaro N">N Decaro</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lin, L" uniqKey="Lin L">L. Lin</name>
</author>
<author><name sortKey="Li, T S" uniqKey="Li T">T.S. Li</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Pan, Y" uniqKey="Pan Y">Y. Pan</name>
</author>
<author><name sortKey="Guan, H" uniqKey="Guan H">H. Guan</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Guan, W" uniqKey="Guan W">W. Guan</name>
</author>
<author><name sortKey="Xian, J" uniqKey="Xian J">J. Xian</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Shen, K" uniqKey="Shen K">K. Shen</name>
</author>
<author><name sortKey="Yang, Y" uniqKey="Yang Y">Y. Yang</name>
</author>
<author><name sortKey="Wang, T" uniqKey="Wang T">T. Wang</name>
</author>
<author><name sortKey="Zhao, D" uniqKey="Zhao D">D. Zhao</name>
</author>
<author><name sortKey="Jiang, Y" uniqKey="Jiang Y">Y. Jiang</name>
</author>
<author><name sortKey="Jin, R" uniqKey="Jin R">R. Jin</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wang, Z" uniqKey="Wang Z">Z. Wang</name>
</author>
<author><name sortKey="Chen, X" uniqKey="Chen X">X. Chen</name>
</author>
<author><name sortKey="Lu, Y" uniqKey="Lu Y">Y. Lu</name>
</author>
<author><name sortKey="Chen, F" uniqKey="Chen F">F. Chen</name>
</author>
<author><name sortKey="Zhang, W" uniqKey="Zhang W">W Zhang</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wu, Y C" uniqKey="Wu Y">Y.C. Wu</name>
</author>
<author><name sortKey="Chen, C S" uniqKey="Chen C">C.S. Chen</name>
</author>
<author><name sortKey="Chan, Y J" uniqKey="Chan Y">Y.J Chan</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wong, K T" uniqKey="Wong K">K.T. Wong</name>
</author>
<author><name sortKey="Antonio, G E" uniqKey="Antonio G">G.E. Antonio</name>
</author>
<author><name sortKey="Hui, D S" uniqKey="Hui D">D.S. Hui</name>
</author>
<author><name sortKey="Lee, N" uniqKey="Lee N">N. Lee</name>
</author>
<author><name sortKey="Yuen, E H" uniqKey="Yuen E">E.H. Yuen</name>
</author>
<author><name sortKey="Wu, A" uniqKey="Wu A">A. Wu</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Chung, M" uniqKey="Chung M">M. Chung</name>
</author>
<author><name sortKey="Bernheim, A" uniqKey="Bernheim A">A. Bernheim</name>
</author>
<author><name sortKey="Mei, X" uniqKey="Mei X">X. Mei</name>
</author>
<author><name sortKey="Zhang, N" uniqKey="Zhang N">N. Zhang</name>
</author>
<author><name sortKey="Huang, M" uniqKey="Huang M">M. Huang</name>
</author>
<author><name sortKey="Zeng, X" uniqKey="Zeng X">X. Zeng</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lei, J" uniqKey="Lei J">J. Lei</name>
</author>
<author><name sortKey="Li, J" uniqKey="Li J">J. Li</name>
</author>
<author><name sortKey="Li, X" uniqKey="Li X">X. Li</name>
</author>
<author><name sortKey="Qi, X" uniqKey="Qi X">X Qi</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Shi, H" uniqKey="Shi H">H. Shi</name>
</author>
<author><name sortKey="Han, X" uniqKey="Han X">X. Han</name>
</author>
<author><name sortKey="Zheng, C" uniqKey="Zheng C">C Zheng</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Xie, X" uniqKey="Xie X">X. Xie</name>
</author>
<author><name sortKey="Zhong, Z" uniqKey="Zhong Z">Z. Zhong</name>
</author>
<author><name sortKey="Zhao, W" uniqKey="Zhao W">W. Zhao</name>
</author>
<author><name sortKey="Zheng, C" uniqKey="Zheng C">C. Zheng</name>
</author>
<author><name sortKey="Wang, F" uniqKey="Wang F">F. Wang</name>
</author>
<author><name sortKey="Liu, J" uniqKey="Liu J">J Liu</name>
</author>
</analytic>
</biblStruct>
</listBibl>
</div1>
</back>
</TEI>
<affiliations><list><country><li>République populaire de Chine</li>
</country>
<settlement><li>Pékin</li>
</settlement>
</list>
<tree><country name="République populaire de Chine"><noRegion><name sortKey="Xu, Yu Huan" sort="Xu, Yu Huan" uniqKey="Xu Y" first="Yu-Huan" last="Xu">Yu-Huan Xu</name>
</noRegion>
<name sortKey="An, Wei Min" sort="An, Wei Min" uniqKey="An W" first="Wei-Min" last="An">Wei-Min An</name>
<name sortKey="Dong, Jing Hui" sort="Dong, Jing Hui" uniqKey="Dong J" first="Jing-Hui" last="Dong">Jing-Hui Dong</name>
<name sortKey="Dong, Li" sort="Dong, Li" uniqKey="Dong L" first="Li" last="Dong">Li Dong</name>
<name sortKey="Gao, Bu Lang" sort="Gao, Bu Lang" uniqKey="Gao B" first="Bu-Lang" last="Gao">Bu-Lang Gao</name>
<name sortKey="Lv, Xiao Yan" sort="Lv, Xiao Yan" uniqKey="Lv X" first="Xiao-Yan" last="Lv">Xiao-Yan Lv</name>
<name sortKey="Ma, Xi" sort="Ma, Xi" uniqKey="Ma X" first="Xi" last="Ma">Xi Ma</name>
<name sortKey="Yin, Xiao Ping" sort="Yin, Xiao Ping" uniqKey="Yin X" first="Xiao-Ping" last="Yin">Xiao-Ping Yin</name>
<name sortKey="Zhang, Hong Jie" sort="Zhang, Hong Jie" uniqKey="Zhang H" first="Hong-Jie" last="Zhang">Hong-Jie Zhang</name>
<name sortKey="Zhang, Jian Zeng" sort="Zhang, Jian Zeng" uniqKey="Zhang J" first="Jian-Zeng" last="Zhang">Jian-Zeng Zhang</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/2020/Analysis

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000836 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/2020/Analysis/biblio.hfd -nk 000836 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    SrasV1
   |flux=    2020
   |étape=   Analysis
   |type=    RBID
   |clé=     PMC:7102535
   |texte=   Clinical and computed tomographic imaging features of novel coronavirus pneumonia caused by SARS-CoV-2
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/2020/Analysis/RBID.i   -Sk "pubmed:32109443" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/2020/Analysis/biblio.hfd   \
       | NlmPubMed2Wicri -a SrasV1

This area was generated with Dilib version V0.6.33.
Data generation: Tue Apr 28 14:49:16 2020. Site generation: Sat Mar 27 22:06:49 2021

Serveur d'exploration SRAS

Clinical and computed tomographic imaging features of novel coronavirus pneumonia caused by SARS-CoV-2

Clinical and computed tomographic imaging features of novel coronavirus pneumonia caused by SARS-CoV-2

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration SRAS
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.